Friday, 24 March 2017

Breast Pain Cancer

pedram: hi everyone, back with dr. sara gottfried,going to talk about an interesting topic today, hi doc.sara: hi, howã­s everybody. hi, pedram. pedram: hello, nice to see you, so we gota lot of really good feedback from the endocrine disruptor segment that we did and so i knowitã­s been taken us as a while to get together and start these, but now weã­re going to beon regular schedule with them. iã­m excited and everyone out there is excited becausei keep getting emails from people saying, ã¬hey, when are you going to do another onewith dr. sara,ã® so here we are. sara: here we are, yeah, weã­re on the schedule.pedram: one of the things that you and iã­ve just chatted about and itã­s a big deal inthe media right now, is this whole breast

cancer deal thatã­s happening.sara: oh yes, yes. pedram: angelina jolie is out there doingpreventative stuff and taken a really bold choice for this and so itã­s been all overthe media, so i wanted to kind of tease it out today because itã­s obviously cancer isalive and well in a lot of ways and itã­s been kind of picking up steam in a lot ofplaces because of the toxic environment that weã­re in. but, i want to kind of demystifysome of this stuff that is out there and just talk about the science a little bit and thenwe could talk about where people are at. we get a bunch of questions too, so we couldmaybe field some questions later after the show.sara: love that. iã­d love to start off with

some stats just the fact that one in two americansis affected by cancer. itã­s a little bit higher in men. it can sometimes average outto one in three women, one in two men if you divide it up, but i agree with you. this isa big topic, angelina really brings it to the surface because sheã­s so glamorous andshe wrote the new york times op-ed piece, where she described this decision to removeher breasts prophylactically because of the gene that she carries. iã­m super happy tobe talking about this today. pedram: fantastic, there is a lot of stuff,there is a lot of talk on the establishment side, how this is going to save lives, howthis is absolutely the way of the future and then there is talk on the other side saying,ã¬look this is super expensive and the people

that could afford it are the only ones thatcan get it and frankly the people that are going to lose their lives to this wonã­t beable to do the testing and itã­s going to cause a ripple in the healthcare system thatã­sjust not going to be sustainable.ã® i know there is a lot of angles to this, but letã­sjust start off with what the risks are, i mean there are so many toxins out there, thereare so many environmental factors, but weã­re not talking about those here per se. whatweã­re talking about is genomic stuff, genetic predisposition. iã­d love for you to kind of tease that outa little bit prior to us getting into the whole cancer story.sara: sure, well i think angelina really described

it best. what she said she was facing whenshe made this decision to remove her breasts prophylactically was greater than an 80% riskover her lifetime to breast cancer. now, most women have a one in eight chance of developingbreast cancer. angelinaã­s risk is considerably higher, so thatã­s what tipped the balancefor her. she has, as she described it, the faulty gene and that is the brca1 gene, whichputs you at a greater risk for both breast and ovarian cancer.pedram: now, there is testing that will be done for this, itã­s not cheap, itã­s aboutthree grand or more, which obviously is an obstacle for many women, but once you testedpositive for this, i mean for her, itã­s an 80% chance, which is huge. if those were yourodds in vegas, youã­d bet on it every time

and if theyã­re not, you bet against it. thoseare huge odds. sara: thatã­s right, yeah and i think anotherimportant point pedram is that women need more choices, not fewer and so the peoplewho are arguing against her making this decision and sort of saying, ã¬thatã­s fine, youã­rein this elite status, you have the money to spend on this procedure.ã® i actually thinkthat women need more choices, not fewer, men too. i think itã­s really powerful that sheshared her story so publicly and brought this into the spotlight because really this isgoing to come back to things that are near and dear to our heart, which is how do youcreate the good neighborhood for your dna. itã­s not so much that she need to dial inevery single gene and what is exactly your

percentage risk, but i think, weã­ve got tolook at this piece of how do you create the best neighborhood, how do you not have thesort of problems that make you spiral down toward cancer and instead have a much morevirtuous cycle happening in your body. pedram: well, amen to that. i mean thatã­slots of stuff that we can really do stuff about. i canã­t control who i was born toand the genes that we come in with, but the epigenetic expression of that stuff thatã­swhere we can actually have an effect on our health and what we can do. i mean itã­s arguablethat with this brca1 and brca2, she could fully express in the negative light and allthat. i mean thatã­s where all the debate is right now, but the point is that we havea lot that we can do to offset some of these

tendencies and setup that neighborhood. maybewe should talk about some of these just kind of key practices that will help clean up theneighborhood. sara: yeah, so clean up the neighborhood.well, if we just start with breast cancer, i think itã­s so important to realize thatweã­ve dialed this in pretty well, like we know how you can reduce your risk. i liketo start off by saying we know that 50 to 80% of your dna and how itã­s expressed isdetermined by how you eat, move, think and supplement. i mean this is a really majorconcept that also is [inaudible 00:05:54] vitality. what are some of those things, whenit comes to breast cancer prevention, we know that a low-fat diet actually makes a difference.itã­s painful for me to even say that because

i think fat is so important, but it showstime and time again that a low-fat diet makes difference. you can sort of think about the japanese andhow the japanese have such low rates of both prostate and breast cancer. fat does seemto play a role with them. we also know that fiber is super important. i feel like fiberis the unsung hero. we all need about 40 to 50 g of fiber a day and i think of that asa pound of vegetables, get your pound of vegetables every day. most of us need some additionalfiber beyond that. but, pedram how about you, youã­ve got some strategies that i know youbelieve in. pedram: thereã­s so many to look at in termsof just like you said, how you eat, sleep,

supplement, take care of yourself and allthat. first and foremost, are you hydrated, are your detox pathways working correctlyand thatã­s something that we see a lot of in clinic. as people come in and a lot oftheir detoxification pathways, there you go, exactly, i got mine here.sara: everybody drink your water right now. pedram: drink your water while youã­re listeningto this, exactly and so just keeping it flowing and keeping it through, i mean the world isnã­tgetting any cleaner and so we get this brown cloud of mercury coming over from china andwe got diesel, smoke and all sorts of stuff in our own neighborhoods. working and havingcruciferous vegetables, having things that will help the liver, pull this junk out ofthe system and out through the bowel or out

to the uterine, whatever we can do to detoxand sweat or get it out, fantastic thatã­s the work that we can do on the frontend. butlike you had mentioned, you make the choices of what goes into your body at the grocerystore and then eventually you make them at home. itã­s really what youã­re buying offthe shelves. i mean i just had jeffrey smith over herein the office last week and talking about gmos and what these kind of nasty foods thatare out there that are frankenfoods are doing to our bodies that are big question mark really.lot of it, we donã­t even know whatã­s happening and what we do know is happening is kind ofscary. for us and the stance that i would take like clinically is always just go asclean and organic and fresh as you can and

go through every single cupboard in your houseand go through pantries and all stuff, just get out all the junk. itã­s kind of like ifyou are trying to get out of debt, first thing you do is you cut up your credit cards. youcanã­t ã– sara: clear the decks, clear the decks.pedram: thatã­s right. sara: get all that crap out of your kitchen,i love it. start a revolution with your grocery card, yes.pedram: thatã­s right, thatã­s right and you and i talk about this a lot is you vote withyour dollars, so youã­ll vote for not just the good sustainable companies that are doinggood work and providing clean food and just not being jerks on the planet by buying theirproducts and supporting them, but youã­re

also voting for your own health with everyhealthy item that youã­re putting into your body. the front-end of all of this i thinkis on the food and the stuff that goes into your body and into your house, into your environment.from there, god forbid these types of things come up, then thereã­s interventions and thereã­scomplementary types of treatment that will work with certain things. i mean for angelina, this is all preventativereally, i mean from what i understand there was no cancer diagnosis. that was just a predisposition.sara: thatã­s correct. pedram: thatã­s a bold stance, but i meanagain 80% is a pretty solid number. sara: it is a solid number and for the detractors,the people who are criticizing angelina, i

just wanted to share a story and i hear thesestories almost every day in my practice. i have a woman who is 56 years old who is positivefor the same gene that angelina has and she has been getting digital mammograms everysix months for like 26 years and she has been getting mris of her breasts pretty routinely.she has gone through about seven biopsies and every time she has a biopsy, she has gotthat anxiety thatã­s normal, where you just feel like, ã¬this is the time that i didnã­tescape my fate.ã® i think itã­s really important to realizethat we want more choices, like itã­s really valuable to understand that these are reallygood choices for creating the best neighborhood and theyã­re certainly affordable to buy broccolias opposed to prophylactic mastectomy. there

is quite a difference in terms of the cost,but i also think that itã­s so important to realize that there is also a cost to all ofthat diagnostic testing that angelina needs or other people need who are at greater risk.thatã­s one piece i wanted to share. i also wanted to dial in a little bit more on thefood and drink side, which you can do for preventing cancer. you mentioned that cruciferousvegetables, i love vegetables. i think this is such an important message,but i also just want to give the caveat that if you have thyroid problems, you got to bekind of cautious about it. i donã­t think the data is very strong, but there is thislong history of how raw brassica, raw cruciferous vegetables like broccoli and brussels sproutsand so on can slow down your thyroid. i think

actually this problem is more related to gmosoy speaking of jeffrey smith, but itã­s important to realize that it may cause a problem. ithink overall the benefit is still there from getting all the nutrients that you get fromyour vegetables, but itã­s just something to think about if you have thyroid issues.then also can i just say a little something about alcohol.pedram: please do. sara: we know that when it comes to breastcancer, this is such sad news. we know that three to six servings a week of alcohol islinked to a greater risk of breast cancer. this is tied to the point you made pedramabout the detoxification because we know that women who drink more, who have more than threeto six servings a week, estrogen in their

body will do a backflip and cause problems,lead to damaged dna, lead to turning off the protective genes and turning on those badneighborhood genes. we donã­t want that, so you want to also modify how much alcohol youare having. this is one of those things that women hate to hear, men too. but my messageis drink less better quality. how is that pedram?pedram: fair enough, well some people need and iã­d like to just kind of stay on thispoint for a second, some people need that glass or two of wine a night to decompress.for me i always stop and say, ã¬look itã­s just because people havenã­t been taught decompressionrituals in our culture.ã® you grow up in asia or something, your grandpa taught you howto meditate or do tai chi out in the yard.

you grow up somewhere where you can go outand take a walk in the woods. i mean you grew up in alaska, you know what itã­s like tobe out in nature. a lot of people i think do a stress decompression ritual. look, cortisolis not your friend and cortisol is oftentimes causing all kinds of problems as youã­ve writtenabout. this is a huge part of the whole hormone imbalance thing with people in stress. people try to bring down their stress withalcohol. i think that thereã­s healthier ways to do so and ways that will make you feelbetter in the morning. sara: so true and the very thing you thinkyouã­re getting from the alcohol, itã­s actually backfiring on the other side. we know thatalcohol actually raises your cortisol. you

think that youã­re using it to decompressand yeah it feels a little good when you have a buzz, but itã­s also robbing you of thesleep that you need at night. you may fall asleep more easily but the quality is notgoing to be good, so we need to really look at that. iã­m glad you mentioned it and ifyou donã­t have grandfather that taught you meditation, learn it on your iphone. thereã­sall these apps that you can use and in five minutes while youã­re sitting at the grocerystore in line, causing a revolution with your grocery card, do a little five minutes onyour iphone and it will make a big difference. pedram: bingo i know itã­s something thatmy wife and i always bicker about. sheã­s like, ã¬why you keep buying all these kookyapps.ã® itã­s like theyã­re so great. in the

old days, you got to climb up some templeand spend three months of your life trying to figure out how to breathe through yourbelly and now you can just download it off your phone.sara: itã­s so true, you donã­t have to move to the himalayas.pedram: itã­s true and frankly, i did that. i traveled through the himalayas and iã­lltell you, you have this kind of pseudo-enlightened feeling when youã­re up there because itã­sbeautiful and everyone is nice, but then when you come back and youã­re sitting in rushhour traffic and thereã­s smog and like angry people all around you, thatã­s where the rubberhits the road. if you canã­t learn to meditate down here, youã­re screwed because the cityis chasing out the himalayas. the city is

growing, we got to learn how to deal withstress wherever weã­re at. that i think kind of takes us back to the breast cancer topic,which is you know these environmental toxins are stressors. internal stress is a stressor.i mean this is the neighborhood that you talk about. if you are in a upset neighborhood, thereã­smore chance to have things go wrong and so one of the things in terms of lifestyle thatwe harp on all the time in our content is, happy people are healthier people and justworking to get yourself into a place of meaning and purpose and finding the little thingsthat make you happy and not being upset, keeping up with the joneses or whatever it is thatã­sstressing people out in the neighborhood here.

but then, itã­s also the internal dynamicsof the environment. are there herbs, are there supplements, i mean is there anything elsethat you would recommend? i mean, i know on the eastern side of the spectrum, we talkabout adaptogenic herbs and the ginsengs and the silk worms and all that kind of stuff.weã­ve used that for years. what would you recommend to people?sara: well, you touched on a really important point, which is the role of stress and cortisoland your adaptability and how that plays in with creating a good neighborhood or the neighborhoodthatã­s going to take you down that path toward cancer. youã­re absolutely right. in factthe latest research, i was just talking to the head of psychiatry at stanford about thisparticular topic because theyã­ve published

some studies looking at how women who arebreast cancer survivors have whatã­s called a flat cortisol curve. normally, youã­re supposedto have your peak cortisol first thing in the morning, kind of like a downhill ski slopefrom there, thatã­s normal. peak is within about an hour from waking up in the morning. breast cancer survivors tend to have thisreally flat line, where they donã­t peak first thing in the morning. they have some issueswith their cortisol levels and there is many ways to increase your adaptability, so beyondmeditating or using inner balance on the iphone or going to yoga class, there are some adaptogenicherbs. iã­m a big fan of rhodiola. thatã­s one of my favorites. my particular issue,which i discovered 10 years ago, is high cortisol.

iã­m a just a bit of a stress junky, probablyhappened in my residency training. iã­m sure you know nothing about that pedram.pedram: never been stressed before in my life. sara: no, no youã­ve never had high cortisol,so yeah, so i like rhodiola because it helps you adjust your high cortisol, it brings itdown into that goldilocks position of not too high and not too low. but, share someof the herbs that you like for creating a good neighborhood.pedram: well, rhodiola, the tibetan rhodiola in particular, i used to play with [inaudible00:17:55] and they do all kind of adaptogenic herbs for rock stars and stuff like that.again, now weã­re kind of talking about high ended expensive stuff, itã­s like youã­regoing to take this brca gene thing for three

grand, if you could afford some of these herbs,then awesome, good for you. but, i love basic kind of adaptogenic stuff. you can even getan american ginseng that works really well. weã­ve toyed with holy basil for cortisollevels, which seems to work pretty well, like [inaudible 00:18:26] and stuff like that.sara: yes. pedram: great. one of the things that thechinese use a lot is just mint, mint teas helps kind of move the liver and clear theliver. itã­s worked tremendously well, but again when i have someone coming in with cortisolissues, first thing i do is ask them, ã¬hey, are you moving.ã® because if you are goingfrom office job to home to tv show to reading on your ipad in bed and wondering why youã­renot falling asleep, then we have to have a

whole other conversation. i get them out,i get them moving, i get them exercised in a circadian rhythm, where theyã­re doing itin the morning and then in the evening, theyã­re kind of doing more decompressive stuff. i find that that works really well, sure thereã­spills and potions for stuff, but just that kind of good old healthy living and movingthe human animal the way it should, iã­m finding is working really well for our patients aswell. sara: yeah, i love that and as usual youã­resupported by the best evidence. we know that holy basil, asian ginseng, rhodiola, theyare all supported by randomized trials and they really show that they create a good neighborhood.then there is whole movement thing, i mean

you raise this whole issue of circadian rhythmthat i think is so important. this is going to be the next 10 years of research. i wastalking to susan love who is one of the authorities on breast cancer and she wrote the dr. susanlove breast book that sold millions of copies. she was saying to me, ã¬we used to think ofbreast cancer as being this cell that would mutate and it would have daughter cells andover two years, it would become a lamp or you would see it on the mammogram, we donã­tthink about it that way anymore.ã® we think about creating the good neighborhood versusthe bad neighborhood and the good neighborhood has a really clear circadian rhythm, whereyouã­re in bed within a few hours of the sun going down, youã­re not getting a ton of artificiallight at night, youã­re not watching [inaudible

00:20:20] tablet for hours on an end, whichwe know reduces your melatonin, another thing that we see in breast cancer survivors. you are catching angel train, youã­re goingto bed by 10 oã­clock and youã­re getting up at the same time each morning, somewhereclose to when the sun comes up, that sets in your brain, in your pineal gland, whereyou make melatonin and also between the hypothalamic pituitary adrenal axis, known as hpa for short,thatã­s where you setup your circadian rhythm. a good circadian rhythm is so important. whenyou have a dis-circadian rhythm or youã­re not having it, youã­re staying up too late,youã­re on the laptop, whatever it is, youã­re not moving, youã­re not getting the brightlight that helps you set your circadian rhythm,

thatã­s where things start to come unraveled.pedram: i mean, for me, iã­m kind of lucky. i live in southern california, the sunã­sout, itã­s beautiful all the time. i mean you lived in alaska for a while. i mean therhythms get a little funky when youã­re up in northern altitudes and stuff like that.i know that thereã­s light boxes and kind of full-spectrum light devices that have workedpretty well. for me, what i do here in california is simple, i prescribe camping therapy. getout in the woods, like wake up with the sun, do it a few nights in a row, your body willremember and then when you come back, stick to it. i just basically ixnay the tv at nightfor patients and say, ã¬look thatã­s it, no artificial light at night.ã®

but, what do you do for people who donã­treally have the kind of natural bounty if you will or if itã­s just freezing and coldall the time and they canã­t really get out and do stuff like that, do you have supplementsthat you recommend? sara: well, there are a few supplements thati think are helpful for setting the circadian rhythm, but i actually still think that yourpoint about movement is really important. even in alaska, when i was living there, ican think back to when i was 13 years old. in the wintertime, you get about 18 hoursof darkness, so that means that the sun sort of comes up around 11 and then it goes downby like five. thatã­s not many hours to set up your circadian rhythm, but we would gocross-country skiing. we would go in the darkness.

every golf course in alaska has turned intoa cross-country ski resort and so we would cross-country ski, weã­d go on bike trails. we would get out and the movement really helpedwith setting the circadian rhythm, so yes you can use light boxes, you can use supplements.iã­m a fan of, for people who have like a flat line, when it comes to their cortisollevels, i think that licorice can be really effective. you just have to be careful withit because it can raise your blood pressure as you know pedram. we just know the vitaminb is really important and getting sufficient omega-3, sometimes threonine can be helpfulin terms of helping you with focus and with reduce in anxiety. thereã­s lots of differentways to take care of that circadian rhythm.

but, a big part of it is making sure thatyouã­re sleeping at night and you donã­t have erratic sleep cycles.pedram: thatã­s kind of a big subject obviously because i think that people in the westernworld are progressively getting worse and worse sleep. you go home with all the worriesof the world on your mind. things cost money and you keep spending it. itã­s becoming anepidemic. i know you and i are going to be talking about sleep a lot more often. look,i still come from the school of thought that i could pretty much sleep anything off. itã­sjust great medicine and we know now that the melatonin and some of the things that arehappening in the brain that are getting out there that are kind of super immunomodulatorsare coming in and really cleaning up the shop

at night while weã­re sleeping. if youã­re not in deep sleep, youã­re nothitting stage iv, youã­re not going to some of these places where growth hormone is hittingand some of the things that you and i know biochemically are working. but, at the endof the day, where the rubber hits the road is do you wake up feeling refreshed, do youwake up feeling better and if the answer is no, then you got to look at your sleep.sara: absolutely, if your first thought when you wake up is either snooze button or howfast can i get some coffee, we need an intervention, so i totally agree with that. i also thinkitã­s important to realize that as you get older, you will fall down a hormonal flightof stairs, male or female, if you donã­t master

your sleep. as you just said, it is whereall the repair that happens in your body in terms of growth hormone, testosterone, havinga repair conversation between your brain and your adrenal glands and your heart that happensat night. i think this is a really essential piece that people master their sleep.pedram: when we talk about breast cancer and the term hormones, everyone is so freakedout about hormones because they all think that hormones are going to cause cancer andthat they got to control things. obviously if you have estrogen sensitive ones that people,everyone is running away from soy and all that, so itã­s become this huge thing thateveryone is freaked about. can we talk about that for a second, just in terms of hormonehealth and cancer?

sara: sure, well itã­s not so much that anyof these hormones are evil or dangerous. itã­s more of that when theyã­re out of balancethat can cause problems. what i find in my practice is that somewhere around 70 to 80%of women between the ages of 35 and 50 have estrogen dominance. now, men can have estrogendominance too and iã­ll get to that in a moment. but, when it comes to women and breast cancer,we know that estrogen dominance is a risk factor for breast cancer. how do you measurethat? you actually measure on day 21 if youã­re still cycling or any time after menopause.the ratio between progesterone and estradiol and if itã­s less than a 100, that means youã­reestrogen dominant. you can also do it based on your symptomsand i have a quiz that people can use to figure

out if they have estrogen dominance. thereã­slots of different symptoms including breast tenderness and moodiness, pms, also knownas pass my shotgun. we want to make sure that weã­ve gotten estrogen imbalance. when estrogenis hanging out in the body too long and that can be purely from the food that youã­re eatingor not eating. if estrogen is hanging out too long in the body and stimulating the estrogenreceptors thatã­s where you have the bad neighborhood that can lead to breast cancer. we know that eating commercial meat actuallychanges your [inaudible 00:27:02]. it makes more of those bad bacteria that donã­t loveyou, that are not your best friend as michael pollan would say. we also know if youã­renot getting enough fiber, as we talked about

earlier that can lead to not having estrogenget used and remote, which is what we want. now, with the guys, whatã­s important is yourratio of testosterone to estrogen. if you have too much estrogen because it starts torise as guys get older and testosterone declines, you can have the classic symptoms of estrogendominance. you can have man boobs, love handles, you lose your drive, you may not have as muchsexual interests. these are not good, we donã­t want those things.we want to manage these ratios for both men and women.pedram: thatã­s obviously beyond the scope of what we want to talk about today, but maybewe should do a whole show on figuring out how people can get to that solution. i meanyouã­d be saving a lot of marriages with this

conversation here.sara: well, not just that. there was just some new data looking at testosterone to estrogenratios and heart disease in men, so yes we definitely have to do a whole session on that.pedram: fantastic, okay, so just to wrap this up because i donã­t want to go too long onthis because i know people are on their drive and are getting where theyã­re getting whateverit is right now. long story short ã– sara: theyã­re going to go home and meditate.pedram: go home and meditate, right, exactly. sara: de-stress.pedram: de-stress, eat will, take care of yourself. angelina is brave for doing whatshe did. people have reacted in different ways guys, but i think i definitely side withwhat youã­re saying is, i think women need

more choices. i think humans need more choicesand itã­s just one more thing that we could do. now, if youã­re talking about [inaudible00:28:49] genetics and all this kind of like, ã¬oh, theyã­re going to force this stuff onthe government.ã® thereã­s all sorts of talk out there. at the end of the day, you andi can only look at this as clinicians and say, ã¬whatã­s best for the patient, i donã­twant to get into the politics of any of this.ã® whatã­s best for the patient is, the sooneryou know the better. if you know your odds, then you know how to live your life accordingly. but for those of you who could say, ã¬okay,iã­m going to take this test, iã­m going to spend the three grand and it turns out thatbrca gene isnã­t an issue for me.ã® it doesnã­t

mean little debbies, oreos and six-pack ofbeer every night because youã­re going to set up a neighborhood thatã­s still goingto screw it up, all right. sara: you still need a good neighborhood evenif you donã­t have the cancer genes, absolutely. pedram: yeah, i mean just donã­t mess withit, donã­t tempt fate. sara: well, exactly, just a quick stat onthat. we know that 80% of women who develop breast cancer, donã­t have the genetics thatput them at increased risk. we are talking to 80% of people still need to create thegood neighborhood. itã­s really important. pedram: yeah, absolutely. i think next week,weã­ll kind of segue into this because next week, weã­re going to do a segment on autismand some of the environmental toxins out there

and some of the increased chances of developingsome of these things. again, guys, itã­s an environmental, itã­s how we live. i donã­tthink we could hammer that point home hard enough. itã­s how we live, so the cleaneryou can live, the healthier you are, the more youã­re aware of your neighborhood, the better.sara, i know, you have hormone quiz, so iã­ll get the url from you and weã­ll post it withthis so that people can have the tools and everything that they need for this. anythingelse that you have in terms of resources and things that could be helpful for people onthis particular topic? sara: well, this is one of those topics iwonã­t shut up about because i think itã­s so important and i would just add that wetalked last time about endocrine disruptors

and weã­re going to talk again about those.itã­s sort of a thread through all the conversations that we have. just a reminder, some of thethings we talked about last time especially the thyroid, the thyroid plays a key rolewhen it comes to prevention of breast cancer and prevention of other types of cancer. itrules the metabolism in your body and how fast or slow you burn calories. we talkedlast time about getting an organic mattress if you can afford it as a way of avoidingsome of those thyroid disruptors. i just wanted to check in, has anyone gottentheir organic mattress, thatã­s the last little piece i wanted to add on.pedram: awesome, yeah, at the end of the day, guys, weã­re not doing this to look blue inthe face for no reason. we are doing this

to help you guys, so do it, feel the difference,feel better and youã­ll know. one of the topics we do talk about is increased release of toxinsonce people lose weight and how that slows down the thyroid. there is some more on thatthat iã­ll bring up for a subsequent conversation as well. there is a bunch of cool stuff thati think ã– i just donã­t get to see your face enough.sara: i know. pedram: weã­ll keep doing this, so okay, dr.sara gottfried, one of my favorite people on the planet, always a pleasure. i look forwardto our next encounter, so weã­re on to do this weekly, right.sara: you got it, you got my commitment pedram. youã­re one of my favorite people too, sothanks everybody.

pedram: thank you, see you guys soon.sara: all right, bye. pedram: bye.

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